Herpes Simple Virus Type II is capable of eluding vaccines that utilize the body’s adaptive immune response. Yale Professor of Immunobiology Akiko Iwasaki and her research group have discovered a network of immune cells that provides sustained protection at the site of infection, suggesting a more effective approach to vaccine development.
Recent studies in the field of microbiology have overturned prior beliefs on the mechanism of action of antibiotics. These findings hold promise for the future development of antibiotic drugs for combatting the rise in superbugs worldwide. But first, the mystery surrounding antibiotics must be solved.
A team of researchers recently elucidated the structure and dynamics of the HIV fusion machine, which the virus uses to infect human beings. This exciting discovery, published in both Science and Nature, is a potential breakthrough for HIV vaccine development.
Tim Newhouse, Assistant Professor of Chemistry, plans to uses neuroactive molecules from natural products to probe the mysterious mechanisms of memory and cognition in the brain.
Scientists at Yale University, led by Dr. Rajita Sinha, have shown that males and females respond differently to cocaine addiction treatment. Females have higher rates of success on various drugs while males are harder to treat.
“A small molecule found in bacteria and plants is capable of causing major changes in gene expression in response to environmental conditions. Researchers in the Steitz Lab at Yale have solved a long-standing puzzle by figuring out how it works.”
It turns out that small molecules from your buffer can alter millisecond motions of enzymes. A recent study conducted by the Loria lab demonstrates this phenomenon and emphasizes how buffers can confound biochemical experimentation.
Professor Joan A. Steitz has been selected to receive the 2013 Grande Médaille from the French Academy of Sciences.
Yale Professor Ronald Breaker is investigating and isolating regulatory mechanisms hidden in sections of RNA previously labeled as “junk.” His study of these mechanisms, called riboswitches, is yielding a better understanding of the evolutionary history of life on earth.
Professor Joan Steitz, Sterling Professor of Molecular Biophysics and Biochemistry, recently received two major awards for her achievements as a woman scientist.