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Tag "Biology"

A “Beta” Way to Treat Type I Diabetes: A Sweet Discovery

A “Beta” Way to Treat Type I Diabetes: A Sweet Discovery

Diabetes is caused by the immune system’s attack on its own beta cells. Yale researchers have uncovered a population of beta cells resistant to these immune attacks, providing hope for those with Type I diabetes.

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It’s Not Just in Your Head

It’s Not Just in Your Head

Yale researchers have discovered a method of identifying prenatally damaged neurons that become susceptible to mental disorders after birth.

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If It’s Broke, Don’t Fix It: Curing Brain Cancer by Preventing DNA Repair

If It’s Broke, Don’t Fix It: Curing Brain Cancer by Preventing DNA Repair

Broken DNA can put us on the path towards fixing cancer. Research by Peter Glazer and Ranjit Bindra of the Yale Cancer Center suggests that carcinogenic mutations most current therapies aim to repair can instead serve as selecting agents for better drug targeting with DNA repair inhibitors.

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The Clock Keeps Ticking: How the circadian clock helps regulate gene expression

The Clock Keeps Ticking: How the circadian clock helps regulate gene expression

Normal physiological function requires the periodic expression of genes corresponding roughly to a 24 hour cycle. Researchers from the University of California have investigated the molecular nature of the circadian clock responsible for coordinating activity levels of genes to the day-night cycle.

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SNAREs: Optimizing Membrane Fusion Understanding the importance of fusion activation energy

SNAREs: Optimizing Membrane Fusion Understanding the importance of fusion activation energy

A recent measurement of the activation energy of spontaneous membrane fusion has important implications for understanding how membrane fusion is optimized in cells.

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Cracking The Code of mRNA Regulation

Cracking The Code of mRNA Regulation

Yale researchers have developed a technique to decode a heretofore-undeciphered language – that which governs the survival and destruction of our transcriptomes.

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Reading Your Annotated Code: Mapping cytosine methylation with Nanopore sequencing

Reading Your Annotated Code: Mapping cytosine methylation with Nanopore sequencing

DNA methylation plays an important role in gene expression and cancer, and a new paper in Nature Methods presents a novel method for determining methylation sites using Nanopore sequencing.

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Silly Bacteria: Tricks are for Kids

Silly Bacteria: Tricks are for Kids

The influence of pathogens, either directly or indirectly, to manipulate vector microbiota for their own benefit, has not been very well described. This study has demonstrated that a pathogen can effectively “trick” vector microbiota and enhance infection. This allows better colonization of the vector.

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High School Profile: Sasha Thomas

High School Profile: Sasha Thomas

Sasha Thomas is a high school student challenging herself through research and biology competitions.

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Bull’s Eye: Targeted Immunotherapy of Myasthenia Gravis

Bull’s Eye: Targeted Immunotherapy of Myasthenia Gravis

Myasthenia gravis is a motor disease, starting with muscular pain and potentially escalating to failure of vital muscles such as the diaphragm. Like other autoimmune diseases, it was historically treated with steroids, which suppress the immune system overall. Professor Richard Nowak at the Yale School of Medicine has found a much more targeted attack strategy.

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