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Tag "Genetics"

Finding Hidden Cancer Cells: New Study Mobilizes the Immune System to Find Undetectable Cancer Cells

Finding Hidden Cancer Cells: New Study Mobilizes the Immune System to Find Undetectable Cancer Cells

Immunotherapy has become a new tool for treating cancer.  Using the processes that attack pathogens, researchers have discovered treatments that in some patients’ transform cancers from life threatening to manageable conditions.  However, in many patients with several types of cancer,

The Third Reproductive Organ: Yale Study Reveals the Important of Bone Marrow in Successful Pregnancies

The Third Reproductive Organ: Yale Study Reveals the Important of Bone Marrow in Successful Pregnancies

What if some infertility problems are not just issues with the ovaries or uterus? After decades of groundbreaking research, Yale doctors Hugh S. Taylor and Reshef Tal have discovered that bone marrow might play a part in the success of

Expanding Cancer Immunotherapy Targets

Expanding Cancer Immunotherapy Targets

The human immune system is an arsenal ready to fend off invading pathogens. In recent years, the emerging field of cancer immunotherapy has shown that the immune system can sometimes also fight cancer. Now Yale scientists headed by Sidi Chen,

Yale Team Provides Link Between Cannabis and Aggressive Behavior

Yale Team Provides Link Between Cannabis and Aggressive Behavior

In a new study, Yale researchers have pinpointed a specific gene responsible for regulating cannabis-induced aggression, with strong ramifications for the national discussion of cannabis legalization. Led by Janitza Montalvo-Ortiz, Assistant Professor of Psychiatry at the Yale School of Medicine,

Studying the Few to Serve the Many: Studying the rare Gaucher disease to discover molecular mechanisms behind the common Parkinson’s Disease

Studying the Few to Serve the Many: Studying the rare Gaucher disease to discover molecular mechanisms behind the common Parkinson’s Disease

Yale scientists found two potential enzymes to target via cell therapy to treat the common variety of Parkinson’s disease associated with Gaucher disease. These two enzymes regulate the pathology of the specific lipids that accumulate due to Gaucher disease.

Demystifying the Genes Behind Breast Cancer

Demystifying the Genes Behind Breast Cancer

It’s taken over two decades to fit together pieces of information about the BRCA genes behind breast and ovarian cancer. Researchers in the Sung Lab at Yale University, led by Patrick Sung and Weixing Zhao, have tackled the problem by developing a way to study proteins, which led to discovering the function of BRCA1 and its interaction with other genes in the role of tumor expression.

Science in the Spotlight: How to Tame a Fox (And Build a Dog)

Science in the Spotlight: How to Tame a Fox (And Build a Dog)

They greet their owners at the door with leaps and wagging tails, begging for pats. Read Lee Dugatkin and Lyudmila Trut’s account of how they tamed the fox and why it matters.

How Genes Affect Your Flu Vaccines

How Genes Affect Your Flu Vaccines

A national study has confirmed a genetic link to our bodies’ responses to the flu vaccine. Yale Associate Professor of Medicine Ruth Montgomery explains the significance of this discovery to the future of vaccination.

Not So Tumor Suppressant: How a single gene can both promote and suppress tumor growth

Not So Tumor Suppressant: How a single gene can both promote and suppress tumor growth

Tet2, a gene believed to be a tumor suppressor since 2009, may also have tumor-promoting effects on other types of cancer, raising some interesting questions about what it means to be a tumor suppressor and how Tet2 could affect different cancer treatments.

Giving Genes PiggyBac Rides

Giving Genes PiggyBac Rides

New technology that enables certain segments of DNA to “jump” around the genome via a cut and paste method can serve as a more cost-effective, time-efficient alternative to using STEM cells