Yale professor of chemistry David Spiegel and his company Kleo Pharmaceuticals are working to develop drug platforms that could be revolutionary immunotherapies for treating cancer and infectious diseases. “Kleo” is a synthesis of the names of Spiegel’s wife and son.
The Yale Cancer Biology Institute on West Campus is now the nexus of a new initiative geared towards understanding the dynamic changes in cell behavior that characterize cancer. The Institute, together with its collaborators, was the recipient of a 9.5 million dollar grant from the NIH; the funding may pave the way for more advanced therapies that target metastatic cells.
What can a biologist do with ten million dollars? Find new therapies for cancer? Treat inflammatory illnesses? Fight infectious diseases? Established in 2015, the Program in Innovative Therapeutics for Connecticut’s Health (PITCH) is working to accomplish all of these goals.
Sometimes, when scientists apply the knowledge and methods of one discipline to another, surprising and novel discoveries can manifest. Questions such as “How did each case of cancer come to be?” may benefit from an additional perspective, complementing that of
Have you ever thought about how the human body manages to protect itself from the myriad diseases and infections that could attack its cells at any given moment? The key player in this defense is the immune system, which is
You have just finished watching a great movie on Netflix. However, the night is still young, and you want to watch another movie. But where to start? There are so many different genres…so many different options. Fortunately, Netflix has analyzed
Tackling Inflammation at its Genetic Roots: Applying Personalized Medicine to Autoimmunity and Cancer
Yale researchers, led by professor of medicine Richard Bucala, have discovered that the transcription factor, ICBP90, governs the disease-causing aspect of a key inflammatory gene. This discovery has spurred new drug development efforts for patients of inflammatory and autoimmune diseases as well as cancer.
A team of researchers spanning multiple universities, led by Yale Professor Andre Levchenko, has experimentally quantified some of the methods by which cells communicate.
Sunscreen That Blocks More Than Sun: How a Small-But-Mighty Nanoparticle is Revolutionizing Sun Protection
Think you’re beach ready? Read this first! Yale researchers have developed a new sunblock formula which, unlike typical sunblock, does not sink into the skin and alter DNA.
A recent study led by Yale researchers indicates that the hormone FGF21 may help protect against the collapse of the immune system with age by preventing the degradation of the thymus. This discovery may offer a promising treatment for improving immunity in the elderly, as well as for helping cancer patients following bone marrow transplants.