For parents whose children are at risk of inheriting a mitochondrial disorder, genetic material from a third person can help them conceive a healthy child. Mitochondria are maternally inherited organelles, so if a mother’s mitochondrial DNA is mutated, her children
Luke Dittrich’s new book, Patient H.M.: A Story of Memory, Madness, and Family Secrets, introduces a welcome complexity into simplistic understandings of medical ethics.
As winter settles in, perhaps the only seasonal “foods” more iconic than hot chocolate and s’mores are cough drops and tea. Why do some people want to weather colds holding steaming bowls of comforting soup, while others suffer queasy stomachs
Nanoparticles offer an alternative treatment for administering drugs to cancer patients with ovarian and uterine carcinomas. Yale researchers have demonstrated the efficacy of drug delivery via a bioadhesive class of these nanoparticles.
The biggest epidemic since Ebola has caused a sharp increase in cases of babies being born with abnormally small heads. At Yale, a team of researchers have uncovered the first breakthrough insights into a molecular understanding of how Zika virus causes microcephaly.
Psychiatrists often disagree on the optimal methods of treating mental illnesses, because different patients can present with the same mental illness in different ways. The best approach is likely a combination of several treatments tailored to each specific patient.
Yale professor of chemistry David Spiegel and his company Kleo Pharmaceuticals are working to develop drug platforms that could be revolutionary immunotherapies for treating cancer and infectious diseases. “Kleo” is a synthesis of the names of Spiegel’s wife and son.
The Yale Cancer Biology Institute on West Campus is now the nexus of a new initiative geared towards understanding the dynamic changes in cell behavior that characterize cancer. The Institute, together with its collaborators, was the recipient of a 9.5 million dollar grant from the NIH; the funding may pave the way for more advanced therapies that target metastatic cells.
What can a biologist do with ten million dollars? Find new therapies for cancer? Treat inflammatory illnesses? Fight infectious diseases? Established in 2015, the Program in Innovative Therapeutics for Connecticut’s Health (PITCH) is working to accomplish all of these goals.
Sometimes, when scientists apply the knowledge and methods of one discipline to another, surprising and novel discoveries can manifest. Questions such as “How did each case of cancer come to be?” may benefit from an additional perspective, complementing that of