Microbial populations may have to contend with a macro menace: freeloaders. Yale researchers are probing the economics of bacterial and fungal microbes.
Tag "Molecular Biology"
Research into fruit fly growth hormones has yielded a new understanding of hormonal interactions that could be useful in fighting the growth of cancers in humans.
Patients with atopic dermatitis, also known as eczema, have a unique skin microbiome. Knowing more about the relationship between the microbiome and skin conditions like eczema could result in novel, targeted therapies.
A recent study by Yale researchers found that Borrelia burgdorferi, the causative agent of Lyme disease, exhibits a unique pattern of cell growth, elongating through discrete “hot zones” of cell wall synthesis that mark where daughter cells will divide. This discovery could help yield new, targeted therapies for Lyme disease.
Yale professor of chemistry David Spiegel and his company Kleo Pharmaceuticals are working to develop drug platforms that could be revolutionary immunotherapies for treating cancer and infectious diseases. “Kleo” is a synthesis of the names of Spiegel’s wife and son.
The Yale Cancer Biology Institute on West Campus is now the nexus of a new initiative geared towards understanding the dynamic changes in cell behavior that characterize cancer. The Institute, together with its collaborators, was the recipient of a 9.5 million dollar grant from the NIH; the funding may pave the way for more advanced therapies that target metastatic cells.
The Isaacs Lab on Yale University’s West Campus are recoding the genomes of bacteria so that they are resistant to viral infections. The research could pave the way for more secure biofactories.
Tackling Inflammation at its Genetic Roots: Applying Personalized Medicine to Autoimmunity and Cancer
Yale researchers, led by professor of medicine Richard Bucala, have discovered that the transcription factor, ICBP90, governs the disease-causing aspect of a key inflammatory gene. This discovery has spurred new drug development efforts for patients of inflammatory and autoimmune diseases as well as cancer.
A team of researchers spanning multiple universities, led by Yale Professor Andre Levchenko, has experimentally quantified some of the methods by which cells communicate.
Though we have always known that plants are vital to maintaining good health and preventing diseases, only recently have scientists begun to uncover the mystery and promise lying within their leafy tendrils. Yale professor Nicole Clay and her team of