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Tag "Molecular Biology"

Finding NoBody, Your Cell’s Secret Housekeeping Protein

Finding NoBody, Your Cell’s Secret Housekeeping Protein

This recently discovered microprotein has the ability to remove excess genetic material in cells. Researchers are only beginning to explore its potential.

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The Hunt Is On: Mapping brain patterns during predatory hunting

The Hunt Is On: Mapping brain patterns during predatory hunting

Using a technique called optogenetics, researchers at Yale have identified the region of the brain critical for predatory hunting. At the switch of a button, the researchers manipulated when the docile mice transformed into voracious hunters.

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Micro-microbial Economics: Competition at play in microbial populations

Micro-microbial Economics: Competition at play in microbial populations

Microbial populations may have to contend with a macro menace: freeloaders. Yale researchers are probing the economics of bacterial and fungal microbes.

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Fruit Flies Generate Buzz in Oncology Research

Fruit Flies Generate Buzz in Oncology Research

Research into fruit fly growth hormones has yielded a new understanding of hormonal interactions that could be useful in fighting the growth of cancers in humans.

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Eczema Patients Have a Unique Microbiome

Eczema Patients Have a Unique Microbiome

Patients with atopic dermatitis, also known as eczema, have a unique skin microbiome. Knowing more about the relationship between the microbiome and skin conditions like eczema could result in novel, targeted therapies.

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Unraveling the Mystery of Spirochete Growth

Unraveling the Mystery of Spirochete Growth

A recent study by Yale researchers found that Borrelia burgdorferi, the causative agent of Lyme disease, exhibits a unique pattern of cell growth, elongating through discrete “hot zones” of cell wall synthesis that mark where daughter cells will divide. This discovery could help yield new, targeted therapies for Lyme disease.

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Yale-based Targeted Immunotherapies Receive Funding

Yale-based Targeted Immunotherapies Receive Funding

Yale professor of chemistry David Spiegel and his company Kleo Pharmaceuticals are working to develop drug platforms that could be revolutionary immunotherapies for treating cancer and infectious diseases. “Kleo” is a synthesis of the names of Spiegel’s wife and son.

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Yale Fights Back Against Aggressive Cancers

Yale Fights Back Against Aggressive Cancers

The Yale Cancer Biology Institute on West Campus is now the nexus of a new initiative geared towards understanding the dynamic changes in cell behavior that characterize cancer. The Institute, together with its collaborators, was the recipient of a 9.5 million dollar grant from the NIH; the funding may pave the way for more advanced therapies that target metastatic cells.

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Genetically Programming Virus-Resistant Bacteria:  Combating “Bugs” in Biofactories

Genetically Programming Virus-Resistant Bacteria: Combating “Bugs” in Biofactories

The Isaacs Lab on Yale University’s West Campus are recoding the genomes of bacteria so that they are resistant to viral infections. The research could pave the way for more secure biofactories.

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Tackling Inflammation at its Genetic Roots: Applying Personalized Medicine to Autoimmunity and Cancer

Tackling Inflammation at its Genetic Roots: Applying Personalized Medicine to Autoimmunity and Cancer

Yale researchers, led by professor of medicine Richard Bucala, have discovered that the transcription factor, ICBP90, governs the disease-causing aspect of a key inflammatory gene. This discovery has spurred new drug development efforts for patients of inflammatory and autoimmune diseases as well as cancer.

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