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Posts From Charlie Musoff

Macrophage Messengers: Specialized immune cells as targets for metabolism in aging

Macrophage Messengers: Specialized immune cells as targets for metabolism in aging

The communication between the nervous, immune, and metabolic systems changes as people age. A team led by Christina Camell and Vishwa Deep Dixit of the Yale School of Medicine discovered a subset of macrophages at this intersection that could open the door for new strategies to keep people healthier longer.

The Search: Mathematical model explains diversity in cancer cell movement

The Search: Mathematical model explains diversity in cancer cell movement

If cancer cells can’t find the highways of the body, they can’t spread and become more lethal. A mathematical model developed by Andre Levchenko and JinSeok Park of the Yale Systems Biology Institute provides a framework to explain cell migration behavior that can be implemented down the line to keep cells searching longer.

If It’s Broke, Don’t Fix It: Curing Brain Cancer by Preventing DNA Repair

If It’s Broke, Don’t Fix It: Curing Brain Cancer by Preventing DNA Repair

Broken DNA can put us on the path towards fixing cancer. Research by Peter Glazer and Ranjit Bindra of the Yale Cancer Center suggests that carcinogenic mutations most current therapies aim to repair can instead serve as selecting agents for better drug targeting with DNA repair inhibitors.

The Powerpuff Sponges: Sea sponges solve problems in structural engineering

The Powerpuff Sponges: Sea sponges solve problems in structural engineering

Deceptively flimsy, sea sponges may just be the key to stronger and more effective material design. Michael Monn and Haneesh Kesari investigated the structure properties of the rod-like spicules that give the sponges their shape and found that their tapered shape makes them 33% less likely to buckle under pressure.

Yale Landscape Lab Builds Its New Home: New outpost of Urban Farm pushes for community involvement

Yale Landscape Lab Builds Its New Home: New outpost of Urban Farm pushes for community involvement

Over on West Campus is Yale’s Landscape Lab, a new home base for the Urban Farm. Director and recent graduate of the Yale School of Forestry and Environmental Studies, Justin Freiberg hopes to create a space in which environmental research can flourish.

Lucy [Falling Through] the Sky with Diamonds: Compressive fractures suggest cause of early hominin’s death

Lucy [Falling Through] the Sky with Diamonds: Compressive fractures suggest cause of early hominin’s death

One of the oldest cold cases in history is the death of Lucy, the 3.2-million-year-old hominin. John Kappelman, who completed his undergraduate training at Yale, did some detective work on Lucy’s skeleton; an analysis of her bone fractures revealed that she may have died from falling out of a tree.