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Sneaking Organs Past the Immune System

Sneaking Organs Past the Immune System

How to prevent those lucky enough to receive a transplant from losing them The diagnosis comes in: patient X has end-stage renal failure. His kidneys no longer work, and he has the choice of either staying hooked up to a

Divergence

Divergence

The Molecular and Cellular Basis of the Human Brain Evolution Millions of years have passed since humans parted ways with our closest nonhuman primates on the evolutionary pathway. During this time, humans have developed languages and writing skills, harnessed fire

Drop the Broom: Inhibiting a Housekeeping Enzyme to Treat Diseases

Drop the Broom: Inhibiting a Housekeeping Enzyme to Treat Diseases

Delivering therapeutic treatments to cancer, diabetes, and neurodegenerative targets Within our bodies’ cells, a myriad of chemical reactions orchestrate life. These reactions ensure our health and are essential to all of our bodily functions, including metabolism and homeostasis within the

Article: Braving the Cold

Article: Braving the Cold

A genetic adaptation makes certain squirrels and hamsters immune to the cold You step outside of your building, bundled up in four different layers and a marshmallow coat. Buried beneath scarves, hats, and gloves, it’s still not enough to keep

Studying the Few to Serve the Many: Studying the rare Gaucher disease to discover molecular mechanisms behind the common Parkinson’s Disease

Studying the Few to Serve the Many: Studying the rare Gaucher disease to discover molecular mechanisms behind the common Parkinson’s Disease

Yale scientists found two potential enzymes to target via cell therapy to treat the common variety of Parkinson’s disease associated with Gaucher disease. These two enzymes regulate the pathology of the specific lipids that accumulate due to Gaucher disease.

Tracking Transition: From dinosaurs to birds, brain-skull evolution

Tracking Transition: From dinosaurs to birds, brain-skull evolution

New discovery in skull and brain development has implications for greater understanding of evolution of reptiles and birds.

Demystifying the Genes Behind Breast Cancer

Demystifying the Genes Behind Breast Cancer

It’s taken over two decades to fit together pieces of information about the BRCA genes behind breast and ovarian cancer. Researchers in the Sung Lab at Yale University, led by Patrick Sung and Weixing Zhao, have tackled the problem by developing a way to study proteins, which led to discovering the function of BRCA1 and its interaction with other genes in the role of tumor expression.

Guide to the Galaxy: A SAGA: Neighboring galaxies provide clues to the nature of the universe

Guide to the Galaxy: A SAGA: Neighboring galaxies provide clues to the nature of the universe

The Milky Way Galaxy has long been studied as a model for other galaxies in the universe. However, Yale professor Marla Geha is part of a collaboration exploring just how different the Milky Way might actually be.

Macrophage Messengers: Specialized immune cells as targets for metabolism in aging

Macrophage Messengers: Specialized immune cells as targets for metabolism in aging

The communication between the nervous, immune, and metabolic systems changes as people age. A team led by Christina Camell and Vishwa Deep Dixit of the Yale School of Medicine discovered a subset of macrophages at this intersection that could open the door for new strategies to keep people healthier longer.

Putting a Patch on Resistance: A total synthesis of pleuromutilin opens the door to new long-lasting antibiotics

Putting a Patch on Resistance: A total synthesis of pleuromutilin opens the door to new long-lasting antibiotics

Researchers in the Herzon lab at Yale have devised a total synthesis of the antibiotic pleuromutilin, opening the door to new potential antibiotics to help fight bacterial resistance.